We seem to have intermittent connectivity issues client to server. Progress bars will just show connecting and just not do anything, sometimes it will eventually throw up and error that "the server can't be reached at this time".
I can contact the server through ssh and remote desktop with no problem. Memory seems not to be an issue, nor processors; they seem to be at a reasonable state. The logs are either no help, or I am not looking for the right things.

Can anyone give me some direction on where to look and what to look for?

750 users
Version 4.5.6_GA_1044.MACOSXx86 Jul 6, 2007
OS X 10.4.10
2 x 2 GHZ Dual Core Intel Xeon, 6 GB RAM