I've added an rt pipe script to /etc/aliases:

support: "|/opt/zimbra/rt-mailgate --queue Support --action correspond --url http://support.suretecsystems.com/"

and I can see the /etc/aliases is a symlink to:

/etc/aliases -> /opt/zimbra/postfix/conf/aliases

I've also run:

/opt/zimbra/postfix/sbin/newaliases -vvvv

All looks good. This is on ZCS 5.0.8 Open Source Edition.

the host name is mail.suretecgroup.com

and a test to support@mail.suretecgroup.com just bounces.

How do you set aliases up like this?

Should support@any_normal_domain_alias.com work that you define via the Admin Panel?