i have making an upgrade from 7.2.4 on Centos 6.4 to 8.0.4 on the same server
no problème for the upgrade, but afer a few moment
we have some errors

the mail from Outlook and ZCS are blocked, Desktop and Webmail also

the error : com.zimbra.common.service.ServiceException: system failure: Unable to send message

in mailbox.log :

com.zimbra.common.service.ServiceException: system failure: Unable to send message
ExceptionId:qtp74250619-246:https://10.10.12.111:443/service/soa...82535768acce23
Code:service.FAILURE
at com.zimbra.common.service.ServiceException.FAILURE (ServiceException.java:258)
at com.zimbra.cs.mailbox.MailSender.sendMimeMessage(M ailSender.java:692)
at com.zimbra.cs.mailbox.MailSender.sendMimeMessage(M ailSender.java:448)
at com.zimbra.cs.service.mail.SendMsg.doSendMessage(S endMsg.java:232)
at com.zimbra.cs.service.mail.SendMsg.handle(SendMsg. java:166)
at com.zimbra.soap.SoapEngine.dispatchRequest(SoapEng ine.java:522)
at com.zimbra.soap.SoapEngine.dispatch(SoapEngine.jav a:385)
at com.zimbra.soap.SoapEngine.dispatch(SoapEngine.jav a:258)
at com.zimbra.soap.SoapServlet.doWork(SoapServlet.jav a:293)
at com.zimbra.soap.SoapServlet.doPost(SoapServlet.jav a:209)
at javax.servlet.http.HttpServlet.service(HttpServlet .java:727)
at com.zimbra.cs.servlet.ZimbraServlet.service(Zimbra Servlet.java:208)
at javax.servlet.http.HttpServlet.service(HttpServlet .java:820)
at org.eclipse.jetty.servlet.ServletHolder.handle(Ser vletHolder.java:652)
at org.eclipse.jetty.servlet.ServletHandler$CachedCha in.doFilter(ServletHandler.java:1320)
at com.zimbra.cs.servlet.RequestStringFilter.doFilter (RequestStringFilter.java:52)
at org.eclipse.jetty.servlet.ServletHandler$CachedCha in.doFilter(ServletHandler.java:1291)
at com.zimbra.cs.servlet.SetHeaderFilter.doFilter(Set HeaderFilter.java:57)
at org.eclipse.jetty.servlet.ServletHandler$CachedCha in.doFilter(ServletHandler.java:1291)
at org.eclipse.jetty.servlets.UserAgentFilter.doFilte r(UserAgentFilter.java:82)
at org.eclipse.jetty.servlets.GzipFilter.doFilter(Gzi pFilter.java:256)
at org.eclipse.jetty.servlet.ServletHandler$CachedCha in.doFilter(ServletHandler.java:1291)
at com.zimbra.cs.servlet.ETagHeaderFilter.doFilter(ET agHeaderFilter.java:45)
at org.eclipse.jetty.servlet.ServletHandler$CachedCha in.doFilter(ServletHandler.java:1291)
at com.zimbra.cs.servlet.ZimbraQoSFilter.doFilter(Zim braQoSFilter.java:114)
at org.eclipse.jetty.servlet.ServletHandler$CachedCha in.doFilter(ServletHandler.java:1291)
at org.eclipse.jetty.servlets.DoSFilter.doFilterChain (DoSFilter.java:473)
at org.eclipse.jetty.servlets.DoSFilter.doFilter(DoSF ilter.java:344)
at org.eclipse.jetty.servlets.DoSFilter.doFilter(DoSF ilter.java:315)
at org.eclipse.jetty.servlet.ServletHandler$CachedCha in.doFilter(ServletHandler.java:1291)
at org.eclipse.jetty.servlet.ServletHandler.doHandle( ServletHandler.java:443)
at org.eclipse.jetty.server.handler.ScopedHandler.han dle(ScopedHandler.java:137)
at org.eclipse.jetty.security.SecurityHandler.handle( SecurityHandler.java:556)
at org.eclipse.jetty.server.session.SessionHandler.do Handle(SessionHandler.java:227)
at org.eclipse.jetty.server.handler.ContextHandler.do Handle(ContextHandler.java:1044)
at org.eclipse.jetty.servlet.ServletHandler.doScope(S ervletHandler.java:372)
at org.eclipse.jetty.server.session.SessionHandler.do Scope(SessionHandler.java:189)
at org.eclipse.jetty.server.handler.ContextHandler.do Scope(ContextHandler.java:978)
at org.eclipse.jetty.server.handler.ScopedHandler.han dle(ScopedHandler.java:135)
at org.eclipse.jetty.server.handler.ContextHandlerCol lection.handle(ContextHandlerCollection.java:255)
at org.eclipse.jetty.server.handler.HandlerCollection .handle(HandlerCollection.java:154)
at org.eclipse.jetty.server.handler.HandlerWrapper.ha ndle(HandlerWrapper.java:116)
at org.eclipse.jetty.rewrite.handler.RewriteHandler.h andle(RewriteHandler.java:317)
at org.eclipse.jetty.server.handler.DebugHandler.hand le(DebugHandler.java:81)
at org.eclipse.jetty.server.handler.HandlerWrapper.ha ndle(HandlerWrapper.java:116)
at org.eclipse.jetty.server.Server.handle(Server.java :369)
at org.eclipse.jetty.server.AbstractHttpConnection.ha ndleRequest(AbstractHttpConnection.java:486)
at org.eclipse.jetty.server.AbstractHttpConnection.co ntent(AbstractHttpConnection.java:944)
at org.eclipse.jetty.server.AbstractHttpConnection$Re questHandler.content(AbstractHttpConnection.java:1 005)
at org.eclipse.jetty.http.HttpParser.parseNext(HttpPa rser.java:861)
at org.eclipse.jetty.http.HttpParser.parseAvailable(H ttpParser.java:240)
at org.eclipse.jetty.server.AsyncHttpConnection.handl e(AsyncHttpConnection.java:82)
at org.eclipse.jetty.io.nio.SslConnection.handle(SslC onnection.java:196)
at org.eclipse.jetty.io.nio.SelectChannelEndPoint.han dle(SelectChannelEndPoint.java:668)
at org.eclipse.jetty.io.nio.SelectChannelEndPoint$1.r un(SelectChannelEndPoint.java:52)
at org.eclipse.jetty.util.thread.QueuedThreadPool.run Job(QueuedThreadPool.java:608)
at org.eclipse.jetty.util.thread.QueuedThreadPool$3.r un(QueuedThreadPool.java:543)
at java.lang.Thread.run(Thread.java:722)
Caused by: com.zimbra.cs.mailbox.MailSender$SafeMessagingExce ption: connect timed out; chained exception is:
java.net.SocketTimeoutException: connect timed out
at com.zimbra.cs.mailclient.smtp.SmtpTransport.protoc olConnect(SmtpTransport.java:185)
at javax.mail.Service.connect(Service.java:295)
at javax.mail.Service.connect(Service.java:176)
at javax.mail.Service.connect(Service.java:125)
at com.zimbra.cs.mailbox.MailSender.sendMessageToHost (MailSender.java:1076)
at com.zimbra.cs.mailbox.MailSender.sendMessage(MailS ender.java:1002)
at com.zimbra.cs.mailbox.MailSender.sendMimeMessage(M ailSender.java:617)
... 56 more


have you a idea ?

Thanks