msg - system failure: missing blob for id: 280, change: 200
code - service.FAILURE
method - ZmCsfeCommand.prototype.invoke
detail - soap:Receiver

Zimbra.log looks like this:

Apr 18 09:43:17 mailbox postfix/postdrop[28066]: warning: mail_queue_enter: create file maildrop/48985.28066: Permission denied
Apr 18 09:43:17 mailbox postfix/postdrop[22245]: warning: mail_queue_enter: create file maildrop/105725.22245: Permission denied
Apr 18 09:43:17 mailbox postfix/postdrop[1959]: warning: mail_queue_enter: create file maildrop/269355.1959: Permission denied
Apr 18 09:43:17 mailbox postfix/postdrop[31166]: warning: mail_queue_enter: create file maildrop/529390.31166: Permission denied
Apr 18 09:43:17 mailbox su[9387]: (pam_unix) session closed for user zimbra
Apr 18 09:43:01 mailbox slapd[8384]: is_entry_objectclass("", "2.5.6.1") no objectClass attribute

Trust me I know its bad.