We're using 6.0.6 OSE. The problem I'm having is with users that have multiple signatures in the web interface. When these users reply to an email, their default signature appears above the message as it's set to do. However, if they choose a different signature from the signature drop-down or a different persona with a different signature, that signature appears below the message. I have checked and verified in their Preferences that all of their signatures are set to go above the message.